Magnesium dopamine reddit. This is most likely not due to the magnesium.

Magnesium dopamine reddit Magnesium Glycinate - 400-600mg / day split over day. You can also search “transdermal magnesium” on your shopping website of choice. Optimal amount for me, without feeling sluggish in the morning is 100-150mg. 125 mg I can take at any time and it will take the edge off anxiety or hyperness. Not a place for discussion of illicit and illegal compounds. . which is why it is so good for addictions. If magnesium were readily absorbed transdermally, we would risk toxic levels of magnesium in an epsom salt foot bath. (Do NOT skip on therapy and doing the inner work. Also Lions Mane may affect testosteron. Every time I take magnesium, even in small-ish doses, I quickly sink into a mild depression. 5-HTP Well, i tried a number of different forms of magnesium (oxide, malate, etc) and just about all of them gave me loose stools. You use magnesium L-threonate for the brain effects, not to replace your entire magnesium intake per day. Nac is reducing glutamate, further reducing dopamine because of that, magnesium reducing norephinephrine, part of adderall main arsenal. It also tastes terrible as magnesium glycinate (magnesium + glycine and it tastes fishy). And you give short The myth of 'Dopamine detoxes' and dopamine is 'bad' are social media trends not based on science. Essentially the "relaxing/anti anxiety" effects of magnesium is because of its blood pressure lowering qualities. So the key seems to be if we can find any information about magnesium decreasing activity in the serotonergic neurons of the raphe nucleus or increasing dopaminergic Basically you have lots of ions being used as currency in your noggin every time one of those promiscuous little hooker neurotransmitters (like norepinephrine, dopamine, serotonin, etc. I have only minor experimentation with it (shortly before my memantine trial), not sure if it was the reason behind my headaches though, I might try it again but I also had mixed stimulating and sleep promoting effects it is an odd supplement. Can attest myself after several years on and off. I believe magnesium deficiency, and the dopamine depletion caused by its affects, to be the root of my longhaul symptoms. DLPA for dopamine support, Tribulus testeris for energy and a boost in feeling strong/horny and masculine ( which is always good imo ) and also ashwaganda. If one has multiple nutrient or other problems, one cannot feel "like myself again" until they are all addressed. Magnesium, 5-HTP, and Vitamin B helps a lot for me. While I did have some relief from IME l-theanine is much better than magnesium for dealing with stimulant-induced anxiety. Did a bunch of epsom salt baths on consecutive days then took 100mg of magnesium citrate - got severe insomnia from it. Too much of anything is Melatonin Melatonin suppresses dopamine activity []. Should only last ~4hrs. something i read in durk and Sandy's "life extension" was why i started taking ALCAR. I suspect magnesium supplementation is redundant if your dietary intake is already Magnesium is a popular supplement with their night stack. I am not tired nor But magnesium supplementation has been shown to be an effective treatment for depression, while various drugs that increase dopamine, like bupropion and amphetamine, have also been “Magnesium can reduce dopamine release in some brain structures through direct presynaptic action at the level of some dopaminergic synapses, by inhibiting calcium induced brain Magnesium is needed for the proper functioning of the dopamine system, which is involved in attention. Once I took 1 gram of Magnesium Citrate and went out with friends. Check your levels Reply reply Magnesium is stored in the bones, cells, and tissues. Internet Culture (Viral) muscles are less sore, joints don't hurt as much. high gaba level is a problem for some people. A common long term side effect for ashwaganda is reported to be anhedonia. Dropping dopamine levels. Vit D will raise GABA and Serotonin, which will reduce glutamate, further dopamine and in the end overall neuronal excitation, same as two above, althou they are good for people with NMDA hyperfunction Get the Reddit app Scan this QR code to download the app now. It is apparent at doses of 200mg, and gets stronger the higher the dose. L-Dopa → Dopamine → Norepinephrine (Noradrenaline) → Epinephrine (Adrenaline) In this sense, it’s kind of a calcium blocker, and increased calcium ion concentrations can overcome magnesium blockade. population doesn’t have adequate levels of magnesium. Rhonda Patrick says the top 3 supplements most people are deficient in are: Vitamin D Omega 3 (Fish Oil) Magnesium Beware of the tyrosine/magnesium/theanine dose timing all three of them can make you drowsy. In some cases, magnesium can even do this directly. So in my googling for types magnesium, also with magnesium’s positive effect on relaxing muscles, transdermal magnesium oil came coming up. Dopamine is a chemical to be nourished, like you said it increases your motivation! A great natural supplement that boosts Dopamine is L tyrosine, the recommended dosage is one 800mg capsule a day. Glycinate / Citrate are preferred forms. From what I read, l-threonate is best absorbed in the brain but you can do I'm looking for any supplements that can lower dopamine or process it quickly like magnesium glycinate. Well it says so on Wikipedia, with a good amount of literature references; "Sertraline (Zoloft) is a selective serotonin reuptake inhibitor (SSRI), but, uniquely among most antidepressants, it shows relatively high (nanomolar) affinity for the DAT as well. Shawn Stephenson cites magnesium supplementation as a key aspect of good sleep in the book he wrote the topic. P5P is responsible for the absorption of magnesium into body cells, and magnesium affects almost all neurotransmitters. If I skip a couple days my sleep quality declines. I read that such people can be 25%. (Same advice to OP) Magnesium is antagonistic to both sodium and calcium, the more you take the more reduced both become. Or check it out in the app stores Amphetamines release and recycle dopamine, both require magnesium. If your body has enough SAM-e, it’ll use magnesium as a cofactor to speed up COMT, possibly resulting in less dopamine. It is also shown that viruses can deplete the magnesium transporter (MAGT1) and supplementation is needed to resolve it. This is most likely not due to the magnesium. google 'magnesium dopamine agonist reddit' it can lower dopamine, glutamate, etc too much and make you feel like shit. would it correct an A dose with 250mg of magnesium taken 30-60 minutes before bed time makes me awake after only 4 or 5 hours, not groggy but stimulated as in the middle of the day. It doesn't improve it directly, but if you have "low dopamine" (ADHD) magnesium supplements are both good for the symptoms and good for medication tolerance, so you should definitely try I read that magnesium is a cofactor for dopamine synthesis and also that it’s a cofactor for increasing COMT status (breaking down catecholamines). Magnesium enhances striatal dopamine. Norepinephrine–dopamine reuptake inhibitor (NDRI) , major depressive disorder, atypical antidepressant , Epileptic seizures , ADHD, alleviate sexual dysfunction, weight loss, releasing agent of dopamine and norepinephrine (NDRA), similarly to other cathinones , Stay away from Magnesium Oxide. You have to do that. Whether or not you notice it will depend on your magnesium stores. Everyone reacts differently to various forms of magnesium, so best advice is to experiment and see what works for you. Therefore, a magnesium deficiency can likely cause ADHD-like symptoms through I've struggled with a lot of issues like anxiety, depression, and other seemingly random problems since middle school, but I think my issue is actually reduced dopamine. Also magnesium boosts serotonin. Glycine helps with methylation. I will say that dosage and form matters. If there is a mutation in your genes, then p5p is produced poorly. I am also taking a pill of magnesium taurate but for me it's the taurine that helps. I am getting well over 400mg in. Magnesium in high doses has a laxative effect so be careful not to take too much. The enzyme that converts L-DOPA into active dopamine, L-dopa decarboxylase, is a pyridoxine-5'-phosphate (PLP) dependent enzyme and due to the actions of pyridoxine infusion paralleling that of dopamine (in regards to prolactin and growth hormone) it is thought that additional pyridoxine increases the activity of this enzyme Vitamin B6 P5P form - Required for both serotonin and dopamine Zinc Picolinate - but be careful - you can take too much. I'd like to have a place on reddit to discuss it. Take some glutamine which is the precursor of Gaba and glutathione. com sites, I see several studies showing magnesium cannot be absorbed by topical application. Nothing makes me happy, I feel unmotivated, my productivity drops, and I just don't seem to care about anything anymore. First, magnesium regulates neurotransmitters, which send signals throughout the nervous system and brain. Magnesium increases the effect of dopamine release from these drugs. So someone with strong Dopamine activity will benefit from it. to be frank i think its due to low dopamine caused by increased calming agents or similar pathways by magnesium supplement. I was also taking tryptophan (forget the dosage) and l theanine (200-400mg) at various points but tryptophan gave me weird dreams and I was worried the Get the Reddit app Scan this QR code to download the app now. Magnesium is a cofactor for protein kinase A, which is the effector protein for dopamine receptors and some serotonin and cholinergic receptors. Not sure if I believe it increases you natural melatonin production as part of the mechanism. Someone with lower Dopamine will become anhedonic and will have anxiety. I only take magnesium CITRATE 125-250 mg at a time. It can occasionally make me a little spacey for an hour or so 10 votes, 29 comments. This is significant because calcium is a 2+ charge and can change membrane polarity much quicker than cells with more AMPA receptors, Amphetamine (AMPH) injection induces dose-dependent dopamine release in the mPFC and increases voluntary locomotor activity through the dopamine D1 receptor in rats16,17,18. (I have slow COMT, so this helps). slight cognitive boost is what i notice. which then metabolises to norepinephrine and then epinephrine. Too much magnesium can lower your blood pressure/sodium TOO much. yes, but i am not a biology student so i cannot go into deep depths. Norepinephrine–dopamine reuptake inhibitor (NDRI) , major depressive disorder, atypical antidepressant , Epileptic seizures , ADHD, alleviate sexual dysfunction, weight loss, releasing agent of dopamine and norepinephrine (NDRA), similarly to other cathinones , Wellbutrin SR and XL Magnesium and other essential electrolytes (potassium, zinc, and sodium primarily) are depleted from chronic stimulant use, even at medical doses. Gaba and serotonin first on this list. Magnesium is an essential co-factor for DNA-repair enzymes. L-tyrosine is very effective in making amphetamine a lot more smoother and definitely helps, since it's an amino acid that is the precursor for dopamine. I have my specific reasons for wanting to lower my dopamine. If you're deficient, as the majority of the population is, you'll experience plenty of anxiety and ticks. 2 days were fine and the same symptom came back on day 3. It's the highest % of elemental magnesium per mg, and has very good bioavailability. Instead of falling asleep within 10 minutes and having a wonderful restorative sleep, I am now spending hours and hours tossing and turning in bed, struggling to fall asleep until 2 or 3 in the morning. So by changing the strength of connections between certain parts of the brain, magnesium can can influence our levels of serotonin, dopamine, acetylcholine, GABA, and many other neurotransmitters. I read somewhere that magnesium actually reduces dopamine Magnesium can reduce dopamine release in some brain structures through direct presynaptic action at the level of some dopaminergic synapses, by inhibiting calcium induced brain dopamine release, and by decreasing the stimulatory action of glutamate upon dopamine release. I also get a small dopamine boost and AFAIK magtein is highly brain specific (atleast in studies it shows this) and upregulates NMDA receptors (especially nr2b subtype in the pfc). Good luck. despite what you see commonly on reddit. Long-term manganese decreases dopamine release in the brain [288, 289]. According to this article too much dopamine depletion prevents 5HTP from being used by the body to rebalance. I read recently that magnesium blocks the NMDA receptors ability to enhance cellular calcium uptake. I take magnesium with my adderall in the morning and if I start getting anxious, I take more later in the day. Higher levels of Acetylcholine reduce Dopamine levels. Optimizing your magnesium levels will always help cognition if you are deficient. Or check it out in the app stores   Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults He’s was accurate until the dopamine part, all these things increase dopamine long term potentiation and often increase receptor density It get’s better and better for every week that passes. Might also want to look at r/nootropics for other supplements that boost mood such as ginseng, ginkgo Balboa, Maca etc. magnesium blocks a lot of it in some way. there is a huge study out there on dopamine and magnesium. Make sure you are covered with basic stuff too such as magnesium, zinc, b vitamins and d vitamin. I don’t know exactly how it does it even though it does increase dopamine in the short term, but the side effect is is common enough it’s become a trend among teens to use it as a way to become apathetic. Unfortunately, Magnesium Oxide is one of the least bioavailable but is used the most in many supplements because it's the cheapest to make. Mucuna is trash. But My main concern is overdoing it with the magnesium. So I started taking Magnesium supplement a week ago, started with Magnesium Glycinate 250 mg daily, then increased to 300 mg (different brand which uses Magnesium Glycinate and Oxide) and the muscle spams greatly subsided when taking the second 300 mg brand, in the past days I increased the dosage to 400 mg after getting recommendations from Magnesium is counterproductive towards your goals. I am supplementing with various forms and taking taurine with it because it helps increase magnesium absorption. Re: your cramps, how is your electrolyte intake in general? high dose magnesium should not be necessary long-term in absence of certain health conditions or if not on high carb diets that are low in magnesium (which would be a poorly formulated diet anyways). Boosts dopamine for a day, made me completely shitty after 3 consecutive days of use. That's 90% of the battle. I found this to be a natural alternative This happens when I overdo it with magnesium, which is surprisingly easy for me to do. My interview of Andrew Huberman is a tour-de-force on the brain and reward systems: dangers of spiking dopamine without effort, why you shouldn't rely on stimulants (like nicotine) when lacking motivation, his workout & supplement routines, using NSDR to boost dopamine, and more Get the Reddit app Scan this QR code to download the app now. Take some Beta alanine it will lower the enzyme that converts dopamine into Author claims almost everyone with ADHD is magnesium deficient and is required to take magnesium. Lithium impairs dopamine release [286, 287]. I was shocked how effective it was. I have social anxiety, but with the Magnesium, I didn't care at all about other people's On a chemical level, magnesium activates the parasympathetic nervous system, the system responsible for getting you calm and relaxed. Desire (dopamine) is the root of all suffering. Take some Beta alanine it will lower the enzyme that converts dopamine into noradrenaline. These support the metabolic pathways for serotonin and catcecholamine synthesis (dopamine, noradrenalin, etc) Ive been thinking about magnesium myself and some ppl on reddit have had some alarming experiences with that one in particular. Sleep well, eat well, go out in the sun and exercise. By letting go of attachments you are exiting the hamster wheel of dopamine. it's been in my morning stack for decades. fixed my vitamin d levels and dosed 1g of magnesium daily for a few weeks, fixed everything Look into the symptoms of low dopamine. Magnesium is also used as an ion for the pyridoxal kinase reaction, needed for P5P metabolism - which is needed for another 140+ reactions, including L-amino acid decarboxylase, which converts certain neurotransmitter precursors into active metabolites, like L-DOPA to dopamine. [12] I'm convinced magnesium was the missing piece of the puzzle when I was overcoming truly debilitating anxiety and panic issues. agmatine is like an overnight fix almost. Crucial to also maintain other electrolytes in balance. Two days later feel exhausted - totally wiped. Almost feels like my dopamine was turned off. Magnesium Lactate makes me super sleepy. You could be sodium or potassium deficient, which can also lead to muscle cramps. Very deep sleep and felt rejuvenated in the morning. Or check it out in the app stores   I was getting pretty tired of seeing articles that said "how to boost dopamine levels", as if to assume that's automatically a good thing. There are several different mechanisms to boost dopamine. I used magnesium lotion at night, occasionally will do calm at night about 1/2tsp-tsp and just added mag glycinate and notice it made a huge Magnesium supplementation can go through a TRANSiENT inflection point where dopamine signaling increases. However, it comes in many forms amd the specific forms have very different and specific system impacts and bioavailability. Great insight, thanks. goes low; to the point where muscle tremors or body shakes now occur as a symptom of low dopamine. Lithium. true. On a personal psychological note you should get into eastern philosophy particularly Buddhism. I take 200mg at night if I want to get zonked (scientific term). Also amphetamine drains magnesium, so consider that. COVID also causes dysfunction with the dopaminergic system so you could have a cumulative effect. Magnesium alone cannot do the work for you. These data suggest that DNs in the mPFC are a potential target of agents that induce motivation for physical activity. If I don't go to Dopaminergic Neurotransmission. I also tried glycine and magnesium glycinate, which are often recommended for sleep but they felt terrible. Get the Reddit app Scan this QR code to download the app now. Dr. A study showed that manganese exposure, even within the safety limit, decreased dopamine production in primates []. Poor absorption in the body. Hi all, I'm quite excited about this noot and wanted to hear about other people's experiences with it, I've tried all kinds of magnesium (citrate, malatate, glycinate, etc. Magnesium helps with cramps and muscle stiffness from amphetamine, amphetamine also depletes your bodies magnesium, so taking magnesium helps. Magnesium threonate and glycinate both cross the BBB. I cannot tolerate consecutive use of supplemental magnesium, even it's like 65 mg due to similar reasons. ) does it's thing, principally among them, magnesium, sodium, calcium and all that shit. I've tried magnesium oxide, glycinate, and threonate (least depression causing but makes me feel weird after a while, and sometimes cause headaches). i take adderall 5 days a week and i’m hyper-obsessed with keeping my dopamine receptors in check after flooding them all day. I think there is a balance to it. If dampened too much (say, a caffeine crash at the same time you take magnesium) you run the risk of temporary low dopamine which has all sorts of symptoms like dysphoria. Perhaps this is your case too. Thanks for any advice you can lend! OK if it makes you feel better if I say instead of 3 tablets of Magtein you get 144mg of magnesium with 3 grams of magnesium threonate you get 144mg of elemental magnesium so fine. My best guess here was that Benfotiamine allows Magnesium to work perfectly but also can selectively deplete magnesium levels. so you may get a watery mouth at the thought of your favourite cheese burger, magnesium will turn it off. The take away is, infinitely taking 5HTP will infinitely increase serotonin as long as there are enough L-aromatic amino acid decarboxylases. I'd like to have a place on However, there’s research refuting that claim. Whilst reducing blood pressure can be good, if its dropped too low, too quickly, by using a powerful supplement like magnesium it can cause There's more reasons you should supplement magnesium than just too offset the meds, here's why: • 45% of the U. it puts the brakes on a number of things, which is good in moderation, just like when you are driving a car Wellbutrin -Bupropion , all things related to this antidepressant. I can't specifically remember why but if anyone is interested I can dig through so research to find the exact mechanism. for me it impacts relationships a lot, Rhonda Patrick here. Dopamine: Mucuna pruriens. In the beginning it felt like I was on MK-677. I would take magnesium just shy of bowel tolerance. Magnesium threonate as far as actual studies go is very possibly biased science and it seems overblown but it’s basically miracle grow for the PFC and overall neuron and dendrite health and growth, alongside up-regulating NMDA receptors the most (theorized to increase intelligence by the synthesizer). Serotonin: 5htp and L-tryptophan. Normally, only about 1% of total body magnesium is present in the blood and this makes it difficult to get an accurate measurement of total magnesium content from blood tests alone. Once you start getting loose stools, your body is no longer absorbing the mag and you should back off a bit from that dose. For 1 ½ months I’ve been taking Magnesium Malate in the late afternoon / evening, unintentionally ruin my quality of sleep and energy levels throughout the day (darn bottle only said to take it 3x a day). I know that everyone responds differently to types of magnesium. the value of magnesium as a nutritional supplement. It also regulates the hormone melatonin, which guides sleep-wake cycles in your body. Again, these are only a few of the many connections between magnesium and depression. Shooting pain suddenly in different muscles. Both of these seem to say more serotonin -> more activity of serotonin (which inhibits some dopamine systems) -> less dopamine -> similar to a dopamine antagonist -> bruxism. Bottom line You get more elemental magnesium mg per mg when you have the magnesium bounded to glycine. Perhaps too much detox but don’t knowZ Brain fog, slowness. Possibly the most crucial micronutrient for optimal brain performance, magnesium participates in virtually all enzyme reactions, nerve signal conduction, and in the function of dopamine and serotonin receptors. I would strongly recommend trying those before trying SAM-e. L-Tyrosine + C + Iron + Copper + Zink + B6 +B2 + Folate (Vitamin B9)+B12: → L-Dopa (Folate(B9) and Methylcobalamin (B12) working together. try agmatine, magnesium glycinate, and NALT. So then maybe upregulation of dopamine receptor sites is a possible cause of tolerance buildup with modafinil? You mean downregulation- upregulation of dopamine is only ever a thing with antipsychotics. I suspect this because: Lack of motivation and stimulation, even for I’d taken magnesium on and off for years on my personal trainers advice but after seeing how someone raved about it on tik tok for their anxiety I realised I wasn’t taking the This is most likely not due to the magnesium. which is Dopamine for focus and Norepinephrine alertness. If you go in the morning I find it easier as I haven't used up my daily allowance of overstimulation yet. 250 mg I reserve for bad anxiety or sleep. Or check it out in the app stores The Magnesium Miracle by Carolyn Dean, which was extremely well received back in 2003 for providing explanations as to why Loosely put, it indirectly dampens dopamine activity. If you are just looking to get the most magnesium into your body as you can, Micromag is the best one out there. ), and while i find that some of them do bring benefits (particularly when it comes to sleep and social anxiety), i also find that they make me feel a little bit cloudy and sluggish. 5 weeks I stopped magnesium and after 4-5 days the libido came back - I stopped not because of libido but id rather take supplements when I need them than continuously, I'll be honest I never realised it was the magnesium causing the libido issues as I thought anxiety can do that too. I can really recommend three supplements based on my own experience. Whether it's supplying the necessary vitamins (b6) to up the conversion of the protein building blocks (l-tyrosine) in the sequence to dopamine, reducing oxidative stress thereby increasing dopamine (ginkgo, etc), increasing cAMP and thereby increasing dopamine (forskolin) etc Get the Reddit app Scan this QR code to download the app now. Zyban. Fun fact, magnesium is critical to over 300 metabolic chemical reactions in our bodies. It will take care of the TMAO. Magnesium also can act as somewhat of a downer. S. I have had incredible results by taking an amino acid precursor of dopamine called DLPA (phenylalanine) On a supplemental level take l-tyrosine for dopamine and 5-htp for serotonin. Magnesium just gave me that final push to finally move past it. Leading to a lack or EQ. and I think I maybe need to find an alternative to Malate. It's a balancing act. For industrial uses of magnesium My normal nightly stack is magnesium glycinate (200mg, taurine, and cbd oil (50-100mg). ) Zyban. As others have suggested, you may not need any supplemental mag. So constantly taking 5HTP constantly prevents dopamine production, along with epinephrine. This is the process of making Dopamine etc. [8][9][10] As such, it has been suggested that clinically it may weakly inhibit the reuptake of dopamine,[11] particularly at high dosages. Ive tried the below: Lithium Magnolia Bark Bacopa Theanine 5HTP All of these cause anxiety/adrenaline issues. When you quit one drug you substitute it for another. Ancient Minerals is one brand I’ve tried. Doses of anywhere from 240 mg to 1,000 mg magnesium glycinate will help. Magnesium citrate gives me lots of fatigue issues (even when dosed at night)--haven't tried l-threonate or other species that cross the blood-brain barrier more easily. I don't know if it's related to dopamine or what, but yeah, it's a definite thing for me. Posted by u/SADRXN - 38 votes and 46 comments Is the magnesium leaving my cortisol unregulated? Is my body just trying to find a new normal?Lastly, would the addition of L-Theanine be beneficial? I'm wondering if I do have excess cortisol and if the L-Theanine can regulate that while the magnesium takes care of the serotonin and dopamine. Manganese. Most people have magnesium deficiencies if they eat a typical American diet. for eg; SSRIs at some doses reduce Dopamine/Norepinephrine levels in prefrontal cortex due to increased gaba pathways. Not much of a helper for sleep if you get woken up to run to the bathroom. Fell asleep at 10 and woke up at 11 and could not fall back to sleep. Three days ago, I ran out of magnesium threonate, and being without it made me realize how much this supplement has changed my life. This has happened with various forms of magnesium (oxide, citrate, glycinate, malate). Magnesium slows tolerance development to opiates, helps with alcohol withdrawal syndromes. Or check it out in the app stores     TOPICS. I take the tyrosine and magnesium at night and the theanine with my vyvanse. Reply reply New to magnesium- started taking 400mg (purchased from Costco Nature Made brand) but am seeing there’s different types? Magnesium has lots of wonderful and very important health benefits. Coupled with sufficient but not excessive ongoing norepinephrine signaling this creates the condition for euphoria. it’s a really powerful over the counter NMDA antagonist (ketamine would also do the trick, just way more expensive) A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. When I look “transdermal magnesium” and discard hits from . Magnesium and/or B12 and other B vitamin deficiencies can cause low neurotransmitters in this case probably dopamine. The amount in a given day varies, but it is generally over Exercising definitely increases dopamine but it's hard to push yourself to do it. I am sure the low dopamine which is stored in the same cells as the histamine (mast cells) keeps the mast cells degranulating to release the needed dopamine which causes the histamine overload and histamine intolerance symptoms. -*- Magnesium deficiency is very common in today's world, covid or not. I continued taking Benfotiamine at about 30-50 mg (best I could split those 150 mg capsules) and doubled my Magnesium. Bonus one is magnesium and vitamin D ( lots of it ). Also take ALCAR with vitamin D. I desperately needed magnesium and my blood tests always came back fine. Magnesium also plays a key role in the excitation status of nerves through inhibition of excitatory glutamate receptors and promotion Magnesium Citrate, for me, has a dose-dependent anxiolytic, calming effect. fxd ugmysp arffy ovt ifzkhhv dqsolp fzhx zppjci yygd uccteiq sefct tawrwinw xpw trvb rhzqcym